Sleep Deprivation: Here’s How Poor Sleep May Hurt Your Heart

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Sleep Deprivation: Here's How Poor Sleep May Hurt Your Heart?

Sleep Deprivation: Here’s How Poor Sleep May Hurt Your Heart


Sleep Deprivation: Here’s How Poor Sleep May Hurt Your Heart.

If you have not been giving your body the amount of sleep it requires there are slight chance you too fall ill unknowingly. According to a previous research in November 26, 2017. A new study explains why your brain feels so foggy if you don’t get enough sleep.

According to researchers, sleep deprivation disrupts our brain cells’ ability to communicate with each other, leading to temporary mental lapses that affect memory and visual perception.

The study’s authors, helps explains why a tired driver would be at risk for causing an accident. Noticing a pedestrian stepping in front of a car, for instance, would take a sleep-deprived driver’s brain longer to register what they’re perceiving.


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But in a new study, researchers said not getting enough sleep is known to raise the risk of heart disease.

The study, conducted in mice, found that fragmented sleep alters the levels of a certain hormone, which in turn, increases production of inflammatory cells in the bone marrow. This inflammation plays a role in the development of atherosclerosis, or hardening of the arteries due to plaque buildup.

Related: Causes Of Sleep Paralysis Syndrome

The findings, published (Feb. 13) in the journal Nature, suggest that proper sleep “protects against atherosclerosis” and, conversely, that disrupted sleep makes the condition worse, the researchers said.

Sleep And The Heart

Your body needs sleep, just as it needs air and food to function at its best. During sleep, your body heals itself and restores its chemical balance. Your brain forges new connections and helps memory retention. Without enough sleep, your brain and body systems won’t function normally. It can also dramatically lower your quality of life. A review of 16 studies found that sleeping for less than 6 to 8 hours a night increases the risk of early death by about 12 percent.

Sleep deprivation prevents your immune system from building up its forces. If you don’t get enough sleep, your body may not be able to fend off invaders. It may also take you longer to recover from illness. Long-term sleep deprivation also increases your risk for chronic illnesses like diabetes and heart disease.

The obvious signs of sleep deprivation are:

  • excessive sleepiness
  • yawning
  • irritability
  • daytime fatigue

If sleep deprivation continues long enough, you could start having hallucinations—seeing or hearing things that aren’t there. A lack of sleep can also trigger mania in people who have manic depression. Other psychological risks include:

  • impulsive behavior
  • depression
  • paranoia
  • suicidal thoughts

In the new study, the researchers looked at mice that were genetically prone to atherosclerosis. Some of the mice were allowed to get a sufficient amount of sleep, while others had their slumber frequently interrupted by a “sweep bar” that automatically moved across the bottom of the cage.

The sleep-deprived mice didn’t experience any changes in weight or cholesterol levels compared with the sleep-sufficient mice. But the sleep-deprived mice did have larger plaques in their arteries and higher levels of inflammation in their blood vessels, compared with the sleep-sufficient mice, the study found.

The sleep-deprived mice also had lower levels of a hormone called hypocretin (also known as orexin) in a part of their brain called the hypothalamus. In humans, hypocretin is thought to promote wakefulness, and levels of the hormone are known to be reduced in people with the sleep disorder narcolepsy.

The researchers found that the drop in hypocretin levels led to an increase in levels of a signalling protein called CSF1, which in turn increased production of inflammatory white blood cells in the bone marrow and accelerated atherosclerosis. What’s more, restoring hypocretin levels in the mice reduced atherosclerosis.

“We have discovered that sleep helps to regulate the production … of inflammatory cells and the health of blood vessels and that, conversely, sleep disruption breaks down control of inflammatory cell production, leading to more inflammation and more heart disease,” the study senior author Filip Swirski, of the Massachusetts General Hospital Center for Systems Biology, said in a statement.

 

 

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